Monday, 28 September 2009

Dihydroergotamine Tartrate




Dihydroergotamine Tartrate may be available in the countries listed below.


Ingredient matches for Dihydroergotamine Tartrate



Dihydroergotamine

Dihydroergotamine Tartrate (BANM) is known as Dihydroergotamine in the US.

International Drug Name Search

Glossary

BANMBritish Approved Name (Modified)

Click for further information on drug naming conventions and International Nonproprietary Names.

Saturday, 26 September 2009

Spaglumic Acid




Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

R01AC05,S01GX03

CAS registry number (Chemical Abstracts Service)

0004910-46-7

Chemical Formula

C11-H16-N2-O8

Molecular Weight

304

Therapeutic Category

Antiallergic agent

Chemical Names

L-Glutamic acid, N-(N-acetyl-L-α-aspartyl)-

N-Acetyl aspartyl glutamic acid

Foreign Names

  • Acidum Spaglumicum (Latin)
  • Spagluminsäure (German)
  • Acide spaglumique (French)
  • Acido espaglumico (Spanish)

Generic Names

  • Acide spaglumique (OS: DCF)
  • NAAGA (IS)
  • F 8610 (IS)

Brand Names

  • Rhinaaxia
    Théa, France


  • Alerbak
    Pfizer, Chile


  • Naabak
    Allergan, Brazil; Pfizer, Argentina; Pfizer, Colombia; Pfizer, Singapore; Pfizer, Venezuela; Thea, Portugal; Théa, France; Théa Pharma, Switzerland


  • Naaxia
    Novartis, Czech Republic; Novartis, Greece; Novartis, Hungary; Novartis, Italy; Novartis, Portugal; Novartis, Romania; Novartis, Slovakia; Novartis, Turkey; Pfizer, Chile; Silroc, Hong Kong; Thea, Spain; Théa, France


  • Naaxiafree
    Théa, France


  • Rhinaaxia
    Thea-F, Italy

International Drug Name Search

Glossary

DCFDénomination Commune Française
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Sunday, 20 September 2009

Flemagon




Flemagon may be available in the countries listed below.


Ingredient matches for Flemagon



Carbocisteine

Carbocisteine is reported as an ingredient of Flemagon in the following countries:


  • Greece

Sobrerol

Sobrerol is reported as an ingredient of Flemagon in the following countries:


  • Greece

International Drug Name Search

Saturday, 19 September 2009

Trabectedin




Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01CX01

CAS registry number (Chemical Abstracts Service)

0114899-77-3

Chemical Formula

C39-H43-N33-O11-S

Molecular Weight

761

Therapeutic Category

Antineoplastic agent

Chemical Name

(1'R,6R,6aR,7R,13S,14S,16R)-6',8,14-Trihydroxy-7',9-dimethoxy-4,10,23-trimethyl-19-oxo-3',4',6,7,12,13,14,16-octahydrospiro[6,16-(epithiopropanooxymethano)-7,13-imino-6aH-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20-1'(2'H)-isoquinolin]-5-yl acetate (WHO)

Foreign Names

  • Trabectedinum (Latin)
  • Trabectedin (German)
  • Trabectédine (French)
  • Trabectedina (Spanish)

Generic Names

  • Trabectedin (OS: USAN)
  • Ecteinascidin 743 (IS)
  • ET 743 (IS: PharmaMar)
  • ET-722 (IS)
  • ET-729 (IS)
  • ET-736 (IS)
  • ET-745 (IS)
  • ET-759A (IS)
  • ET-759B (IS)
  • ET-770 (IS)
  • NSC-648766 (IS)

Brand Names

  • Yondelis
    Pharma Mar, Belgium; Pharma Mar, Norway; Pharma Mar, Slovenia; PharmaMar, Austria; PharmaMar, Switzerland; PharmaMar, Germany; PharmaMar, Spain; PharmaMar, United Kingdom; PharmaMar, Slovakia; PharmaMar S.A., Netherlands; Swedish Orphan, Sweden; Pharma Mar S.AES, Denmark

International Drug Name Search

Glossary

ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Friday, 11 September 2009

Novo Asat




Novo Asat may be available in the countries listed below.


Ingredient matches for Novo Asat



Paracetamol

Paracetamol is reported as an ingredient of Novo Asat in the following countries:


  • Argentina

International Drug Name Search

Tuesday, 8 September 2009

Oncaspar


Generic Name: pegaspargase (Intramuscular route, Intravenous route)

peg-AS-par-jase

Commonly used brand name(s)

In the U.S.


  • Oncaspar

Available Dosage Forms:


  • Solution

Therapeutic Class: Antineoplastic Agent


Pharmacologic Class: Asparaginase (class)


Uses For Oncaspar


Pegaspargase belongs to the general group of medicines known as antineoplastics. It is used with other cancer medicines as a first-line treatment to a certain type of blood cancer called acute lymphoblastic leukemia (ALL). This medicine also treats ALL in patients who have had serious allergic reactions to L-asparaginase .


Pegaspargase seems to interfere with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells also may be affected by pegaspargase, other effects also occur. Some of these effects may be serious and must be reported to your doctor.


Before you begin treatment with pegaspargase, you and your doctor should talk about the good this medicine will do as well as the risks of using it.


Pegaspargase is to be administered only by or under the immediate supervision of your doctor.


This medicine is available only with your doctor's prescription .


Before Using Oncaspar


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Infants up to 1 year of age—Safety and efficacy have not been established.


Children 1 year of age and older—This medicine has been studied in children 1 year of age and older and has not been shown to cause different side effects or problems than it does in adults. In fact, the side effects of this medicine seem to be less severe in children than in adults.


Geriatric


There is no specific information comparing the use of pegaspargase in the elderly with use in other age groups. Safety and efficacy of pegaspargase in the elderly have not been established.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Adenovirus Vaccine Type 4, Live

  • Adenovirus Vaccine Type 7, Live

  • Bacillus of Calmette and Guerin Vaccine, Live

  • Influenza Virus Vaccine, Live

  • Measles Virus Vaccine, Live

  • Mumps Virus Vaccine, Live

  • Rotavirus Vaccine, Live

  • Rubella Virus Vaccine, Live

  • Smallpox Vaccine

  • Typhoid Vaccine

  • Varicella Virus Vaccine

  • Yellow Fever Vaccine

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Anticoagulant therapy (treatment with blood thinners) or

  • Bleeding problems—The chance of bleeding may be increased

  • Blood clots

  • Chickenpox (including recent exposure) or

  • Herpes zoster (shingles)—Risk of severe disease affecting other parts of the body

  • Type 2 diabetes mellitus—The chance of side effects may be increased

  • Infection—Pegaspargase can decrease your body's ability to fight infection

  • Liver disease—Effects of pegaspargase may be increased because of slower removal of this medicine from the body

  • Pancreatitis—The chance of side effects may be increased

Proper Use of Oncaspar


Pegaspargase sometimes is given together with certain other medicines. If you are using a combination of medicines, it is important that you receive each one at the proper time. If you are taking some of these medicines by mouth, ask your doctor to help you plan a way to take them at the right times .


While you are receiving pegaspargase, your doctor may want you to drink extra fluids so that you will pass more urine. This will help prevent kidney problems and keep your kidneys working well.


This medicine often causes nausea and vomiting. However, it is very important that you continue to receive the medicine, even if you begin to feel ill. Ask your health care professional for ways to lessen these effects, especially if they are severe.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


Precautions While Using Oncaspar


It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.


While you are being treated with pegaspargase, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval. Pegaspargase may lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. In addition, other persons living in your household should not take oral poliovirus vaccine, since there is a chance they could pass the poliovirus on to you. Also, avoid persons who have taken oral poliovirus vaccine. Do not get close to them, and do not stay in the same room with them for long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and the mouth.


Pegaspargase can temporarily lower the number of white blood cells in your blood, increasing the chance of getting infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:


  • If you can, avoid people with infection. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or have painful or difficult urination.

  • Check with your doctor immediately if you notice any unusual bleeding or bruising; black tarry stools; blood in urine or stools; or pinpoint red spots on your skin.

  • Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.

  • Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.

  • Be careful not to cut yourself when you are using sharp objects such as safety razor or fingernail or toenail cutters.

  • Avoid contact sports or other situations where bruising or injury can occur.

If pegaspargase accidentally seeps out of the vein into which it is injected, it may damage some tissue and cause scarring. Tell the doctor or nurse right away if you notice redness, pain, or swelling at the place of injection.


This medicine may cause serious allergic reaction. Tell your doctor immediately if you start having trouble breathing, chest tightness, skin rash, or itching while you are receiving this medicine .


Some people who have received this medicine developed pancreatitis (inflammation of the pancreas). Check with your doctor if you experience sudden and severe stomach pain, nausea, vomiting, fever, or chills while on this medicine .


Check with your doctor immediately if you start having increased thirst or hunger, increased urination, pale skin, nausea, sweating, or faintness. This may be signs that you are having problems with the amount of blood sugar in your body .


This medicine may increase your risk of developing serious blood clots. Tell your doctor right away if you develop any sudden and severe headache, arm or leg swelling, shortness of breath, or chest pain .


Oncaspar Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor as soon as possible if any of the following side effects occur:


More common
  • Abdominal or stomach pain

  • blurry vision

  • constipation

  • dry mouth and skin

  • faintness

  • fatigue

  • fruit-like breath odor

  • increased hunger or thirst

  • increased need to urinate

  • nausea

  • skin paleness

  • skin rash

  • sweating

  • troubled breathing

  • unexplained weight loss

  • unusual bleeding or bruising

  • vomiting

Less common
  • Bloating

  • chest pain

  • confusion

  • cough

  • darkened urine

  • difficulty in breathing or swallowing

  • dizziness

  • fast heartbeat

  • fever or chills

  • headache

  • hives or itching

  • indigestion

  • itching, especially of hands and feet

  • loss of appetite

  • numbness, tingling, or swelling in arms or legs

  • pains in stomach, side, or abdomen, possibly radiating to the back

  • puffiness or swelling of the eyelids or around the eyes, face, lips or tongue

  • reddening of the skin, especially around ears

  • shortness of breath

  • swelling of eyes, face, or inside of nose

  • tightness in chest

  • unusual tiredness or weakness (sudden and severe)

  • wheezing

  • yellow eyes or skin

Rare
  • Black, tarry stools

  • blood in urine

  • hoarseness

  • lower back or side pain

  • painful or difficult urination

  • pinpoint red spots on skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • General feeling of discomfort or illness

Less common
  • Anxiety

  • behavior change similar to drunkenness

  • blurred vision

  • cold sweats

  • convulsions (seizures)

  • cool pale skin

  • difficulty in concentrating

  • drowsiness

  • lack of appetite

  • nervousness

  • nightmares

  • pain at place of injection

  • pain in joints or muscles

  • restless sleep

  • shakiness

  • slurred speech


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More Oncaspar resources


  • Oncaspar Side Effects (in more detail)
  • Oncaspar Use in Pregnancy & Breastfeeding
  • Oncaspar Drug Interactions
  • Oncaspar Support Group
  • 0 Reviews for Oncaspar - Add your own review/rating


  • Oncaspar Prescribing Information (FDA)

  • Oncaspar MedFacts Consumer Leaflet (Wolters Kluwer)

  • Oncaspar Concise Consumer Information (Cerner Multum)

  • Oncaspar Monograph (AHFS DI)

  • Pegaspargase Professional Patient Advice (Wolters Kluwer)



Compare Oncaspar with other medications


  • Acute Lymphoblastic Leukemia

Sunday, 6 September 2009

Kayexalate Na




Kayexalate Na may be available in the countries listed below.


Ingredient matches for Kayexalate Na



Polystyrene Sulfonic Acid

Polystyrene Sulfonic Acid sodium salt (a derivative of Polystyrene Sulfonic Acid) is reported as an ingredient of Kayexalate Na in the following countries:


  • Belgium

International Drug Name Search

Moxillin




Moxillin may be available in the countries listed below.


Ingredient matches for Moxillin



Amoxicillin

Amoxicillin trihydrate (a derivative of Amoxicillin) is reported as an ingredient of Moxillin in the following countries:


  • Germany

International Drug Name Search

Saturday, 5 September 2009

Silvaysan




Silvaysan may be available in the countries listed below.


Ingredient matches for Silvaysan



Silibinin

Silibinin is reported as an ingredient of Silvaysan in the following countries:


  • Germany

International Drug Name Search

Friday, 4 September 2009

Hevizos




Hevizos may be available in the countries listed below.


Ingredient matches for Hevizos



Epervudine

Epervudine is reported as an ingredient of Hevizos in the following countries:


  • Hungary

International Drug Name Search