Eryzole

Generic Name: erythromycin and sulfisoxazole (Oral route)

e-rith-roe-MYE-sin eth-il-SUX-i-nate, sul-fi-SOX-a-zole A-se-teel

Commonly used brand name(s)

In the U.S.

• E.S.P.


• Eryzole


• Pediazole

Available Dosage Forms:

• Powder for Suspension

Therapeutic Class: Antibiotic Combination

Chemical Class: Erythromycin

Uses For Eryzole

Erythromycin and sulfisoxazole is a combination antibiotic used to treat ear infections in children. It also may be used for other problems as determined by your doctor. It will not work for colds, flu, or other virus infections.

Erythromycin and sulfisoxazole combination is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not specifically included in product labeling, erythromycin and sulfisoxazole combination is used in certain patients with the following medical condition:

• Sinusitis (sinus infection)

Before Using Eryzole

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in children over the age of 2 months and has not been shown to cause different side effects or problems than it does in adults. This medicine should not be given to infants under 2 months of age unless directed by the child's doctor, because it may cause unwanted effects.

Geriatric

This medicine is intended for use in children and is not generally used in adult patients.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Astemizole


• Bepridil


• Cisapride


• Dihydroergotamine


• Dronedarone


• Ergoloid Mesylates


• Ergonovine


• Ergotamine


• Grepafloxacin


• Levomethadyl


• Mesoridazine


• Methylergonovine


• Methysergide


• Pimozide


• Posaconazole


• Simvastatin


• Sparfloxacin


• Terfenadine


• Thioridazine


• Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acecainide


• Ajmaline


• Amiodarone


• Amisulpride


• Amitriptyline


• Amoxapine


• Apomorphine


• Aprindine


• Arsenic Trioxide


• Asenapine


• Atorvastatin


• Azimilide


• Azithromycin


• Bretylium


• Cerivastatin


• Chloral Hydrate


• Chloroquine


• Chlorpromazine


• Ciprofloxacin


• Citalopram


• Clarithromycin


• Clindamycin


• Clomipramine


• Colchicine


• Crizotinib


• Dasatinib


• Desipramine


• Dibenzepin


• Digoxin


• Diltiazem


• Disopyramide


• Dofetilide


• Dolasetron


• Doxepin


• Droperidol


• Encainide


• Enflurane


• Eplerenone


• Everolimus


• Fentanyl


• Flecainide


• Fluconazole


• Fluoxetine


• Foscarnet


• Gatifloxacin


• Gemifloxacin


• Granisetron


• Halofantrine


• Haloperidol


• Halothane


• Hydroquinidine


• Ibutilide


• Iloperidone


• Imipramine


• Isoflurane


• Isradipine


• Itraconazole


• Ketoconazole


• Lapatinib


• Levofloxacin


• Lidoflazine


• Lopinavir


• Lorcainide


• Lovastatin


• Lumefantrine


• Mefloquine


• Methotrexate


• Moxifloxacin


• Nilotinib


• Norfloxacin


• Nortriptyline


• Octreotide


• Ofloxacin


• Ondansetron


• Oxycodone


• Paliperidone


• Pazopanib


• Pentamidine


• Perflutren Lipid Microsphere


• Pirmenol


• Pitavastatin


• Prajmaline


• Probucol


• Procainamide


• Prochlorperazine


• Promethazine


• Propafenone


• Protriptyline


• Quetiapine


• Quinidine


• Quinine


• Ranolazine


• Risperidone


• Saquinavir


• Sematilide


• Sertindole


• Sertraline


• Sodium Phosphate


• Sodium Phosphate, Dibasic


• Sodium Phosphate, Monobasic


• Solifenacin


• Sorafenib


• Sotalol


• Spiramycin


• Sulfamethoxazole


• Sultopride


• Sunitinib


• Tadalafil


• Tedisamil


• Telavancin


• Telithromycin


• Tetrabenazine


• Theophylline


• Tolvaptan


• Toremifene


• Trazodone


• Trifluoperazine


• Trimethoprim


• Trimipramine


• Troleandomycin


• Vandetanib


• Vasopressin


• Vemurafenib


• Verapamil


• Voriconazole


• Warfarin


• Zolmitriptan


• Zotepine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acetohexamide


• Alfentanil


• Alprazolam


• Anisindione


• Bexarotene


• Budesonide


• Buspirone


• Carbamazepine


• Cilostazol


• Clozapine


• Cyclosporine


• Diazepam


• Dicumarol


• Fesoterodine


• Methylprednisolone


• Midazolam


• Phenprocoumon


• Roflumilast


• Salmeterol


• Sildenafil


• Sirolimus


• Tacrolimus


• Tolterodine


• Triazolam


• Trimetrexate


• Valproic Acid


• Zafirlukast

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Anemia or other blood problems or


• Glucose-6-phosphate dehydrogenase (G6PD) deficiency—Erythromycin and sulfisoxazole may increase the chance of blood problems

• Heart disease—High doses of erythromycin and sulfisoxazole may increase the chance of side effects in patients with a history of an irregular heartbeat

• Kidney disease or


• Liver disease—Patients with liver or kidney disease may have an increased chance of side effects

• Loss of hearing—High doses of erythromycin and sulfisoxazole may increase the chance for hearing loss in some patients

• Porphyria—Erythromycin and sulfisoxazole may increase the chance of a porphyria attack

Proper Use of erythromycin and sulfisoxazole

This section provides information on the proper use of a number of products that contain erythromycin and sulfisoxazole. It may not be specific to Eryzole. Please read with care.

Erythromycin and sulfisoxazole combination is best taken with extra amounts of water and may be taken with food. Additional amounts of water should be taken several times every day, unless otherwise directed by your doctor. Drinking extra water will help to prevent some unwanted effects (e.g., kidney stones) of sulfa medicines.

Do not give this medicine to infants under 2 months of age, unless otherwise directed by your doctor. Sulfa medicines may cause liver problems in these infants.

Use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

Do not use after the expiration date on the label. The medicine may not work properly after that date. Check with your pharmacist if you have any questions about this.

To help clear up your infection completely, keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times, day and night. For example, if you are to take 4 doses a day, the doses should be spaced about 6 hours apart. If this interferes with your sleep or other daily activities, or if you need help in planning the best times to take your medicine, check with your health care professional.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (suspension):
  
  • For infections caused by bacteria:
    
    • Adults and teenagers—This medicine is used only in children.
    
    
    • Children up to 2 months of age—Use is not recommended.
    
    
    • Children 2 months of age and older—Dose is based on body weight:
      
      • For the four-times-a-day dosing schedule
      
      
      • Children weighing less than 8 kilograms (kg) (under 18 pounds): Dose must be determined by your doctor.
      
      
      • Children weighing 8 to 16 kg (18 to 35 pounds): 1/2 teaspoonful (2.5 milliliters [mL]) every six hours for ten days.
      
      
      • Children weighing 16 to 24 kg (35 to 53 pounds): 1 teaspoonful (5 mL) every six hours for ten days.
      
      
      • Children weighing 24 to 32 kg (53 to 70 pounds): 1 1/2 teaspoonfuls (7.5 mL) every six hours for ten days.
      
      
      • Children weighing more than 32 kg (over 70 pounds): 2 teaspoonfuls (10 mL) every six hours for ten days.
      
      
      • For the three-times-a-day dosing schedule
      
      
      • Children weighing less than 6 kg (under 13 pounds): Dose must be determined by your doctor.
      
      
      • Children weighing 6 to 12 kg (13 to 26 pounds): 1/2 teaspoonful (2.5 mL) every eight hours for ten days.
      
      
      • Children weighing 12 to 18 kg (26 to 40 pounds): 1 teaspoonful (5 mL) every eight hours for ten days.
      
      
      • Children weighing 18 to 24 kg (40 to 53 pounds): 1 1/2 teaspoonfuls (7.5 mL) every eight hours for ten days.
      
      
      • Children weighing 24 to 30 kg (53 to 66 pounds): 2 teaspoonfuls (10 mL) every eight hours for ten days.
      
      
      • Children weighing more than 30 kg (over 66 pounds): 2 1/2 teaspoonfuls (12.5 mL) every eight hours for ten days.
      
      
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store in the refrigerator. Do not freeze.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Eryzole

It is very important that your doctor check you at regular visits for any blood problems that may be caused by this medicine, especially if you will be taking this medicine for a long time.

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Erythromycin and sulfisoxazole may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine:

• Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.


• Wear protective clothing, including a hat. Also, wear sunglasses.


• Apply a sun block product that has a skin protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your health care professional.


• Apply a sun block lipstick that has an SPF of at least 15 to protect your lips.


• Do not use a sunlamp or tanning bed or booth.

If you have a severe reaction from the sun, check with your doctor.

Erythromycin and sulfisoxazole combination may cause blood problems. These problems may result in a greater chance of infection, slow healing, and bleeding of the gums. Therefore, you should be careful when using regular toothbrushes, dental floss, and toothpicks. Dental work should be delayed until your blood counts have returned to normal. Check with your medical doctor or dentist if you have any questions about proper oral hygiene (mouth care) during treatment.

Eryzole Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Itching


• skin rash

Less common

• Aching of joints and muscles


• difficulty in swallowing


• nausea or vomiting


• pale skin


• redness, blistering, peeling, or loosening of skin


• skin rash


• sore throat and fever


• stomach pain, severe


• unusual bleeding or bruising


• unusual tiredness or weakness


• yellow eyes or skin

Rare

• Blood in urine


• dark or amber urine


• irregular or slow heartbeat


• temporary loss of hearing (with kidney disease and high doses)


• lower back pain


• pain or burning while urinating


• pale stools


• recurrent fainting


• severe stomach pain


• swelling of front part of neck

Check with your doctor as soon as possible if any of the following side effects occur:

More common

• Increased sensitivity to sunlight

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Abdominal or stomach cramping and discomfort


• diarrhea


• headache


• loss of appetite


• nausea or vomiting

Less common

• Sore mouth or tongue

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Eryzole resources

• Eryzole Use in Pregnancy & Breastfeeding
• Eryzole Drug Interactions
• Eryzole Support Group
• 0 Reviews for Eryzole - Add your own review/rating

• Eryzole Concise Consumer Information (Cerner Multum)


• Pediazole Concise Consumer Information (Cerner Multum)


• Pediazole MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Eryzole with other medications

• Otitis Media

Erbitux

Generic Name: cetuximab (se TUX i mab)

Brand Names: Erbitux

What is cetuximab?

Cetuximab is a cancer medication that interferes with the growth of cancer cells and slows their growth and spread in the body.

Cetuximab is used to treat cancers of the colon and rectum. It is also used to treat head and neck cancer.

Cetuximab may also be used for purposes not listed in this medication guide.

What is the most important information I should know about cetuximab?

Cetuximab is often used in combination with other cancer medications and/or radiation treatments.

You should not use this medication if you are allergic to cetuximab or to mouse protein.

Before receiving cetuximab, tell your doctor if you have heart rhythm problems, congestive heart failure, breathing problems, coronary artery disease, or low levels of potassium or magnesium in your blood.

After your cetuximab infusion, your doctor will need to watch you for about an hour. This is to make sure you do not have any serious side effects from the medicine.

Some people receiving a cetuximab injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel short of breath, weak or dizzy, nauseated, itchy, or have wheezing, noisy breathing, or a hoarse voice during the injection.

To make sure this medication is helping your condition and not causing harmful effects, your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Do not miss any follow-up visits to your doctor. Avoid exposure to sunlight or tanning beds while you are receiving cetuximab and for at least 2 months after your treatment ends. Cetuximab can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What should I discuss with my healthcare provider before I receive cetuximab?

You should not use this medication if you are allergic to cetuximab or to mouse protein.

To make sure you can safely receive cetuximab, tell your doctor if you have any of these other conditions:

• 
  

  heart rhythm problems;

  
  


• 
  

  lung disease or a breathing disorder;

  
  


• 
  

  congestive heart failure;

  
  


• 
  

  coronary artery disease (clogged arteries); or

  
  


• 
  

  an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).

  
  

FDA pregnancy category C. It is not known whether cetuximab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Whether you are a man or a woman, use effective birth control to prevent pregnancy while you are receiving cetuximab, and for at least 6 months after your treatment ends. It is not known whether cetuximab passes into breast milk or if it could harm a nursing baby. You should not breast-feed a baby while you are receiving cetuximab and for at least 60 days after your treatment ends. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

How is cetuximab given?

Cetuximab is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Cetuximab must be given slowly, and the IV infusion can take up to 2 hours to complete. You may be given other medications to prevent certain side effects while you are receiving cetuximab.

Cetuximab is usually given once every week for 6 to 7 weeks or until your body no longer responds to the medication. Follow your doctor's dosing instructions very carefully.

Cetuximab is often used in combination with other cancer medications and/or radiation treatments. You may receive another cancer medicine 1 hour after your cetuximab injection.

After your cetuximab infusion, your doctor will need to watch you for about an hour. This is to make sure you do not have any serious side effects from the medicine.

If you are also being treated with radiation, you will receive your first cetuximab injection 1 week before your radiation treatment. Later doses are usually given 1 hour before radiation treatments.

To make sure this medication is helping your condition and not causing harmful effects, your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Do not miss any follow-up visits to your doctor.

You may need to have blood tests for several weeks after your cetuximab treatment has ended.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your cetuximab infusion.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while receiving cetuximab?

Avoid exposure to sunlight or tanning beds while you are receiving cetuximab and for at least 2 months after your treatment ends. Cetuximab can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Cetuximab side effects

Some people receiving a cetuximab injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel short of breath, weak or dizzy, nauseated, itchy, or have wheezing, noisy breathing, or a hoarse voice during the injection.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

• 
  

  an acne-like skin rash or any severe skin rash;

  
  


• 
  

  redness, swelling, or puffiness under your skin;

  
  


• 
  

  chest tightness, dry cough, wheezing, feeling short of breath;

  
  


• 
  

  feeling like you might pass out;

  
  


• 
  

  chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

  
  


• 
  

  fever, chills, flu symptoms, mouth and throat ulcers, rapid heart rate, rapid and shallow breathing;

  
  


• 
  

  feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or

  
  


• 
  

  slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

  
  

Less serious side effects may include:

• 
  

  dry, cracked, or swollen skin;

  
  


• 
  

  changes in your fingernails or toenails;

  
  


• 
  

  headache;

  
  


• 
  

  diarrhea;

  
  


• 
  

  mild nausea, vomiting, upset stomach;

  
  


• 
  

  sore throat;

  
  


• 
  

  weight loss; or

  
  


• 
  

  weakness.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect cetuximab?

There may be other drugs that can interact with cetuximab. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Erbitux resources

• Erbitux Side Effects (in more detail)
• Erbitux Use in Pregnancy & Breastfeeding
• Erbitux Drug Interactions
• Erbitux Support Group
• 2 Reviews for Erbitux - Add your own review/rating

• Erbitux Prescribing Information (FDA)


• Erbitux Monograph (AHFS DI)


• Erbitux Advanced Consumer (Micromedex) - Includes Dosage Information


• Erbitux Consumer Overview


• Erbitux MedFacts Consumer Leaflet (Wolters Kluwer)


• Cetuximab Professional Patient Advice (Wolters Kluwer)

Compare Erbitux with other medications

• Colorectal Cancer
• Head and Neck Cancer
• Squamous Cell Carcinoma

Where can I get more information?

• Your doctor or pharmacist can provide more information about cetuximab.

See also: Erbitux side effects (in more detail)

Potaba

Generic Name: potassium aminobenzoate (po TAS ee um a MEE noe BEN zoe ate)

Brand Names: Potaba

What is Potaba (potassium aminobenzoate)?

Potassium aminobenzoate is a form of Vitamin B, which supports many important body functions.

Potassium aminobenzoate works by causing a softening of skin or tissues when used over time. It also raises oxygen levels in tissues of the body.

Potassium aminobenzoate is used to treat conditions that cause skin or tissues to harden, including scleroderma (skler-oh-DERM-a), dermatomyositis (der-mat-oh-mye-oh-SYE-tis), and Peyronie's (pe-ROE-neez) disease.

Potassium aminobenzoate may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Potaba (potassium aminobenzoate)?

Before taking this medication, tell your doctor if you have kidney disease, diabetes, or chronic hypoglycemia (low blood sugar).

Tell your doctor if you are taking a sulfa antibiotic, such as Bactrim, Cotrim, Septra, and others.

Take this medicine with a meal or snack. This will help prevent upset stomach, and will keep your blood sugar from getting too low. Tell your doctor if you are on a special diet, or if you need to schedule any other medications around your eating schedule.

Potassium aminobenzoate is usually taken 4 times each day. Follow your doctor's instructions.

Avoid drinking alcohol while taking potassium aminobenzoate. Alcohol can lower your blood sugar. Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of potassium aminobenzoate is not likely to cause life-threatening symptoms, but you may have low blood sugar. Symptoms of low blood sugar include hunger, headache, confusion, irritability, drowsiness, weakness, dizziness, tremors, sweating, and fast heartbeat. If blood sugar gets too low, you may have seizure (convulsions), fainting, or coma (severe hypoglycemia can be fatal).

What should I discuss with my health care provider before taking Potaba (potassium aminobenzoate)?

Before using potassium aminobenzoate, tell your doctor if you are allergic to any drugs, or if you have:

• 
  

  kidney disease;

  
  


• 
  

  diabetes; or

  
  


• 
  

  chronic hypoglycemia (low blood sugar).

  
  

If you have any of these conditions, you may not be able to use potassium aminobenzoate, or you may need dosage adjustments or special tests during treatment.

Potassium aminobenzoate may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether potassium aminobenzoate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Potaba (potassium aminobenzoate)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

The oral powder and tablet forms of this medicine should be mixed with cold water or juice. Crush the tablets before dissolving them in liquid. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

Take this medicine with a meal or snack. This will help prevent upset stomach, and will keep your blood sugar from getting too low. Tell your doctor if you are on a special diet, or if you need to schedule any other medications around your eating schedule.

Potassium aminobenzoate is usually taken 4 times each day. Follow your doctor's instructions.

Store potassium aminobenzoate at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Be sure to take the medicine with food. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

An overdose of potassium aminobenzoate is not likely to cause life-threatening symptoms, but you may have low blood sugar. Symptoms of low blood sugar include hunger, headache, confusion, irritability, drowsiness, weakness, dizziness, tremors, sweating, and fast heartbeat. If blood sugar gets too low, you may have seizure (convulsions), fainting, or coma (severe hypoglycemia can be fatal).

What should I avoid while taking Potaba (potassium aminobenzoate)?

Avoid drinking alcohol while taking potassium aminobenzoate. Alcohol can lower your blood sugar.

Potaba (potassium aminobenzoate) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Take care not to let your blood sugar get too low while you are taking this medicine. You may have hypoglycemia if you take potassium aminobenzoate without food.

Symptoms of low blood sugar include:

• 
  

  hunger, headache, confusion, irritability;

  
  


• 
  

  drowsiness, weakness, dizziness, tremors;

  
  


• 
  

  sweating, fast heartbeat;

  
  


• 
  

  seizure (convulsions); or

  
  


• 
  

  fainting, coma (severe hypoglycemia can be fatal).

  
  

Less serious side effects are more likely to occur, such as:

• 
  

  nausea;

  
  


• 
  

  loss of appetite;

  
  


• 
  

  fever; or

  
  


• 
  

  mild skin rash.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Potaba (potassium aminobenzoate)?

Before using potassium aminobenzoate, tell your doctor if you are using a sulfa antibiotic such as:

• 
  

  Bactrim;

  
  


• 
  

  Cotrim;

  
  


• 
  

  Proloprim;

  
  


• 
  

  Septra;

  
  


• 
  

  SMX / TMP; or

  
  


• 
  

  Trimpex.

  
  

If you are using any of these drugs, you may not be able to use potassium aminobenzoate, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect potassium aminobenzoate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Potaba resources

• Potaba Side Effects (in more detail)
• Potaba Use in Pregnancy & Breastfeeding
• Drug Images
• Potaba Drug Interactions
• Potaba Support Group
• 0 Reviews for Potaba - Add your own review/rating

• Potaba Advanced Consumer (Micromedex) - Includes Dosage Information


• Potaba MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Potaba with other medications

• Dietary Supplementation

Where can I get more information?

• Your pharmacist has information about potassium aminobenzoate written for health professionals that you may read.

See also: Potaba side effects (in more detail)

Edluar

Generic Name: zolpidem (Oral route, Oromucosal route, Sublingual route)

zole-PI-dem

Commonly used brand name(s)

In the U.S.

• Ambien


• Ambien CR


• Edluar


• Zolpimist

Available Dosage Forms:

• Tablet


• Tablet, Extended Release


• Spray

Therapeutic Class: Nonbarbiturate Hypnotic

Uses For Edluar

Zolpidem belongs to the group of medicines called central nervous system (CNS) depressants (medicines that slow down the nervous system). Zolpidem is used to treat insomnia (trouble in sleeping). Zolpidem helps you get to sleep faster and sleep through the night. In general, when sleep medicines are used every night for a long time, they may lose their effectiveness. In most cases, sleep medicines should be used only for short periods of time, such as 1 or 2 days, and generally for no longer than 1 or 2 weeks.

This medicine is available only with your doctor's prescription.

Before Using Edluar

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Sleep medicines may cause a special type of memory loss or "amnesia". When this occurs, a person does not remember what has happened during the several hours between use of the medicine and the time when its effects wear off. This is usually not a problem since most people fall asleep after taking the medicine. In most instances, memory problems can be avoided by taking zolpidem only when you are able to get a full night's sleep (7 to 8 hours) before you need to be active again. Be sure to talk to your doctor if you think you are having memory problems.

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of zolpidem in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of zolpidem in the elderly. However, confusion, dizziness, and falling are more likely to occur in the elderly, who are usually more sensitive than younger adults to the effects of zolpidem. Elderly patients may require a lower dose to help reduce unwanted effects.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Alprazolam


• Buspirone


• Butabarbital


• Chlordiazepoxide


• Chlorpromazine


• Clonazepam


• Clorazepate


• Dexmedetomidine


• Diazepam


• Diphenhydramine


• Doxylamine


• Estazolam


• Eszopiclone


• Ethchlorvynol


• Flumazenil


• Flurazepam


• Fospropofol


• Halazepam


• Hydromorphone


• Hydroxyzine


• Lorazepam


• Meprobamate


• Midazolam


• Oxazepam


• Oxycodone


• Pentobarbital


• Phenobarbital


• Prazepam


• Promethazine


• Propofol


• Quazepam


• Ramelteon


• Secobarbital


• Tapentadol


• Temazepam


• Thioridazine


• Triazolam


• Zaleplon

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Bupropion


• Carbamazepine


• Ciprofloxacin


• Desipramine


• Ketoconazole


• Rifampin


• Sertraline


• St John's Wort


• Telaprevir


• Venlafaxine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Ethanol


• food

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Alcohol abuse, history of or


• Drug abuse or dependence, history of—Dependence on zolpidem may develop.

• Diseases affecting metabolism or disease involving blood circulation—Caution should be used in patients with these medical problems.

• Emphysema, asthma, bronchitis, or other chronic lung disease or


• Mental depression, history of or


• Mental illness, history of or


• Myasthenia gravis (severe muscle weakness) or


• Sleep apnea (temporary stopping of breathing during sleep)—Use with caution. Zolpidem may make these conditions worse.

• Kidney disease or


• Liver disease—Use with caution. Higher blood levels of zolpidem may result, increasing the chance of side effects.

Proper Use of zolpidem

This section provides information on the proper use of a number of products that contain zolpidem. It may not be specific to Edluar. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much is taken, it may become habit-forming (causing mental or physical dependence).

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Take zolpidem just before going to bed, when you are ready to go to sleep. This medicine works very quickly to put you to sleep.

You should swallow the extended-release tablets whole. Do not divide, crush, or chew them.

Do not take this medicine when your schedule does not permit you to get a full night's sleep (7 to 8 hours). If you must wake up before this, you may continue to feel drowsy and may experience memory problems, because the effects of the medicine have not had time to wear off.

Zolpidem should not be taken with food or right after a meal. It will work faster if you take it on an empty stomach. However, if your doctor tells you to take the medicine a certain way, take it exactly as directed.

If you are using the oral spray for the first time, it must be primed by spraying it for 5 times in a safe direction away from your face and other people. If the oral spray has not been used for 14 days, it must be primed again with 1 spray.

To use the oral spray:

• Pull the child-resistant cap to separate it from the base.


• Remove the clear protective cap from the pump.


• Hold the container upright with the black spray opening pointed directly into your mouth.


• Fully press down on the pump to make sure that a full dose (5 mg) of is sprayed directly into the mouth over the tongue. If a 10 mg dose is prescribed by your doctor, a second spray should be given.


• Put the clear protective cap back over the pump after each use.

To use the sublingual tablets:

• Do not open the blister pack that contains the tablet until you are ready to take it. Do not use the tablet if the seal of the blister pack is broken.


• Remove the tablet from the blister pack by peeling back the top layer of paper, then push the tablet through the foil.


• Place the tablet under your tongue. It should melt quickly. Do not crush, chew, or swallow the tablet. Do not eat or drink anything after using this medicine.


• If you are taking Intermezzo®, check the time before you take this medicine. Intermezzo® should be taken only if at least 4 hours of sleep remain before the planned time of awakening.

Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For the treatment of insomnia (trouble in sleeping):
  
  • For oral dosage form (extended-release tablets):
    
    • Adults—12.5 milligrams (mg) once a day at bedtime.
    
    
    • Older adults—6.25 mg once a day at bedtime.
    
    
    • Children—Use and dose must be determined by the doctor.
    
    
  
  
  • For oral dosage form (oral spray):
    
    • Adults—10 milligrams (mg) or 2 sprays into the mouth at bedtime.
    
    
    • Older adults—5 mg or 1 spray into the mouth at bedtime.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  
  • For oral dosage form (sublingual tablets):
    
    • Adults—
      
      • Edluar™: 10 milligrams (mg) placed under the tongue at bedtime.
      
      
      • Intermezzo®: 1.75 mg (for women) and 3.5 mg (for men) placed under the tongue at bedtime.
      
      
    
    
    • Older adults—Intermezzo®: 1.75 mg (for both men and women) placed under the tongue at bedtime.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  
  • For oral dosage form (tablets):
    
    • Adults—10 milligrams (mg) once a day at bedtime.
    
    
    • Older adults—5 mg once a day at bedtime.
    
    
    • Children—Use and dose must be determined by the doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Throw the child-resistant container of the oral spray when the 60 sprays have already been used.

Precautions While Using Edluar

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to check for unwanted effects.

If you think you need to take zolpidem for more than 7 to 10 days, be sure to discuss it with your doctor. Insomnia that lasts longer than this may be a sign of another medical problem.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine.

This medicine may cause some people, especially older persons, to become drowsy, dizzy, lightheaded, clumsy or unsteady, or less alert than they are normally. Even though zolpidem is taken at bedtime, it may cause some people to feel drowsy or less alert on arising. Also, this medicine may cause double vision or other vision problems. Make sure you know how you react to zolpidem before you drive, use machines, or do anything else that could be dangerous if you are dizzy, or are not alert or able to see well.

If you develop any unusual and strange thoughts or behavior while you are taking zolpidem, be sure to discuss it with your doctor. Some changes that have occurred in people taking this medicine are like those seen in people who drink alcohol and then act in a manner that is not normal. Other changes may be more unusual and extreme, such as confusion, worsening of depression, hallucinations (seeing, hearing, or feeling things that are not there), suicidal thoughts, and unusual excitement, nervousness, or irritability.

This medicine may cause sleep-related behaviors such as driving a car (sleep-driving), walking (sleep-walking), having sex, making phone calls, or preparing and eating food while asleep or not fully awake. If these reactions occur, tell your doctor right away.

If you will be taking zolpidem for a long time, do not stop taking it without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping completely. Stopping this medicine suddenly may cause withdrawal side effects.

After taking zolpidem for insomnia, you may have difficulty sleeping (rebound insomnia) for the first few nights after you stop taking it.

If you think you or someone else may have taken an overdose of this medicine, get emergency help at once. Taking an overdose of zolpidem or taking alcohol or other CNS depressants with zolpidem may lead to breathing problems and unconsciousness. Some signs of an overdose are severe drowsiness, severe nausea or vomiting, staggering, and troubled breathing.

Zolpidem may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Stop taking this medicine and call your doctor right away if you have itching; hives; hoarseness; trouble breathing or swallowing; or any swelling of your hands, face, mouth, or throat while you are using this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Edluar Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

• Clumsiness or unsteadiness


• confusion


• mental depression

Rare

• Dizziness, lightheadedness, or fainting


• falling


• fast heartbeat


• hallucinations (seeing, hearing, or feeling things that are not there)


• skin rash


• swelling of the face


• trouble with sleeping


• unusual excitement, nervousness, or irritability


• wheezing or difficulty with breathing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Clumsiness or unsteadiness (severe)


• dizziness (severe)


• double vision or other vision problems


• drowsiness (severe)


• nausea (severe)


• slow heartbeat


• troubled breathing


• vomiting (severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Sleepiness or unusual drowsiness

Less common

• Abdominal or stomach pain


• abnormal or decreased touch sensation


• abnormal sensation of movement


• appetite disorder


• balance disorder


• binge eating


• bladder pain


• bloated


• bloody or cloudy urine


• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings


• change in hearing


• chest discomfort


• chills


• confusion about identity, place, and time


• constipation


• continuing ringing or buzzing or other unexplained noise in the ears


• daytime drowsiness


• diarrhea


• difficult, burning, or painful urination


• difficulty with moving


• difficulty with swallowing


• discouragement


• double vision or other vision problems


• drugged feelings


• dryness of mouth


• ear drainage


• earache


• excess air or gas in the stomach or intestines


• eye redness


• false or unusual sense of well-being


• fear


• feeling of unreality


• feeling sad or empty


• fever


• frequent bowel movements


• frequent urge to urinate


• full feeling


• general feeling of discomfort or illness


• generalized slowing of mental and physical activity


• headache


• hearing loss


• heartburn


• hives or welts


• itching ears


• joint pain


• lack of appetite


• lack of feeling or emotion


• lack or loss of self-control


• lack or loss of strength


• longer or heavier menstrual periods


• loss of balance


• loss of interest or pleasure


• memory problems


• mood swings


• muscle aches, cramping, pain, or stiffness


• nausea


• nervousness


• nightmares or unusual dreams


• pain in the joints


• passing gas


• redness of the skin


• redness or soreness of the throat


• sense of detachment from self or body


• shortness of breath or troubled breathing


• skin rash


• skin wrinkling


• sneezing


• sore throat


• stress symptoms


• stuffy or runny nose


• swollen joints


• tiredness


• trouble concentrating


• trouble with sleeping


• vision blurred


• visual depth perception altered


• vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Edluar side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Edluar resources

• Edluar Side Effects (in more detail)
• Edluar Use in Pregnancy & Breastfeeding
• Edluar Drug Interactions
• Edluar Support Group
• 5 Reviews for Edluar - Add your own review/rating

• Edluar Prescribing Information (FDA)


• Edluar MedFacts Consumer Leaflet (Wolters Kluwer)


• Edluar Consumer Overview


• Zolpidem Prescribing Information (FDA)


• Ambien Consumer Overview


• Ambien MedFacts Consumer Leaflet (Wolters Kluwer)


• Ambien Monograph (AHFS DI)


• Ambien Prescribing Information (FDA)


• Ambien CR Extended-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Ambien CR Prescribing Information (FDA)


• Intermezzo Consumer Overview


• ZolpiMist Consumer Overview


• Zolpimist Prescribing Information (FDA)


• Zolpimist Oral Spray MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Edluar with other medications

• Insomnia

esmolol Intravenous

ES-moe-lol

Commonly used brand name(s)

In the U.S.

• Brevibloc


• Esmolol HCl

Available Dosage Forms:

• Solution

Therapeutic Class: Cardiovascular Agent

Pharmacologic Class: Beta-Adrenergic Blocker, Cardioselective

Uses For esmolol

Esmolol is used to control rapid heartbeats or abnormal heart rhythms. esmolol is also used to treat fast heartbeat and high blood pressure during surgery, after surgery, or during other medical procedures .

esmolol is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart .

esmolol is available only with your doctor's prescription .

Before Using esmolol

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For esmolol, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to esmolol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of esmolol in the pediatric population. Safety and efficacy have not been established .

Geriatric

No information is available on the relationship of age to the effects of esmolol in geriatric patients. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving esmolol .

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving esmolol, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using esmolol with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Albuterol


• Amiodarone


• Arformoterol


• Bambuterol


• Bitolterol


• Broxaterol


• Clenbuterol


• Clonidine


• Colterol


• Diltiazem


• Dronedarone


• Fenoldopam


• Fenoterol


• Formoterol


• Hexoprenaline


• Indacaterol


• Isoetharine


• Levalbuterol


• Metaproterenol


• Pirbuterol


• Procaterol


• Reproterol


• Rimiterol


• Ritodrine


• Salmeterol


• Terbutaline


• Tretoquinol


• Tulobuterol


• Verapamil

Using esmolol with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acarbose


• Aceclofenac


• Acemetacin


• Acetohexamide


• Alclofenac


• Alfuzosin


• Amlodipine


• Apazone


• Arbutamine


• Benfluorex


• Benoxaprofen


• Bromfenac


• Bufexamac


• Bunazosin


• Carprofen


• Chlorpropamide


• Clometacin


• Clonixin


• Dexketoprofen


• Diclofenac


• Diflunisal


• Digoxin


• Dipyrone


• Doxazosin


• Droxicam


• Etodolac


• Etofenamate


• Felbinac


• Felodipine


• Fenbufen


• Fenoprofen


• Fentiazac


• Floctafenine


• Flufenamic Acid


• Flurbiprofen


• Gliclazide


• Glimepiride


• Glipizide


• Gliquidone


• Glyburide


• Guar Gum


• Ibuprofen


• Indomethacin


• Indoprofen


• Insulin


• Insulin Aspart, Recombinant


• Insulin Glulisine


• Insulin Lispro, Recombinant


• Isoxicam


• Ketoprofen


• Ketorolac


• Lacidipine


• Lercanidipine


• Lornoxicam


• Manidipine


• Meclofenamate


• Mefenamic Acid


• Meloxicam


• Metformin


• Mibefradil


• Miglitol


• Morphine


• Morphine Sulfate Liposome


• Moxisylyte


• Nabumetone


• Naproxen


• Nicardipine


• Nifedipine


• Niflumic Acid


• Nilvadipine


• Nimesulide


• Nimodipine


• Nisoldipine


• Nitrendipine


• Oxaprozin


• Oxyphenbutazone


• Phenoxybenzamine


• Phentolamine


• Phenylbutazone


• Pirazolac


• Piroxicam


• Pirprofen


• Pranidipine


• Prazosin


• Propyphenazone


• Proquazone


• Repaglinide


• St John's Wort


• Sulindac


• Suprofen


• Tamsulosin


• Tenidap


• Tenoxicam


• Terazosin


• Tiaprofenic Acid


• Tolazamide


• Tolbutamide


• Tolmetin


• Trimazosin


• Troglitazone


• Urapidil


• Zomepirac

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of esmolol. Make sure you tell your doctor if you have any other medical problems, especially:

• Bradycardia (slow heartbeat) or


• Heart block or


• Heart failure—Should not use in patients with these conditions .

• Diabetes or


• Hypoglycemia (low blood sugar)—May cover up some of the signs and symptoms of these diseases, such as a fast heartbeat .

• Hypotension (low blood pressure)—May worsen this condition .

• Kidney disease—Use with caution. The effects may be increased because of slower removal from the body .

• Lung disease (e.g. asthma, bronchitis, emphysema)—May cause difficulty with breathing in patients with this condition .

Proper Use of esmolol

A nurse or other trained health professional will give you esmolol. esmolol is given through a needle placed into one of your veins .

Precautions While Using esmolol

Your doctor will only give you a few doses of esmolol until your condition improves, and then you will be switched to another medicine that works the same way. If you have any concerns about this, talk to your doctor .

esmolol Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

• Blurred vision


• confusion


• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly


• increased sweating


• unusual tiredness or weakness

Less common

• Itching of skin


• numbness and tingling of face, fingers, or toes


• pain in arms, legs, or lower back, especially pain in calves and/or heels upon exertion


• pale, bluish-colored, or cold hands or feet


• weak or absent pulses in legs

Rare

• Blue lips and fingernails


• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings


• changes in skin color


• changes in vision


• chest pain or discomfort


• convulsions


• coughing that sometimes produces a pink frothy sputum


• decrease in frequency of urination


• decrease in urine volume


• delusions


• dementia


• difficult, fast, noisy breathing, sometimes with wheezing


• difficulty in passing urine (dribbling)


• difficulty with speaking


• feeling of warmth


• feeling unusually cold


• lightheadedness, dizziness, or fainting


• loss of bladder control


• muscle spasm or jerking of all extremities


• no heartbeat


• pain, tenderness, or swelling of foot or leg


• painful urination


• paleness of skin


• peeling of skin


• redness of the face, neck, arms and occasionally, upper chest


• shivering


• shortness of breath


• slow or irregular heartbeat


• small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope


• sudden loss of consciousness


• swelling, redness, or burning of skin where the needle is placed


• tightness in chest

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Dilated neck veins


• extreme fatigue


• irregular breathing


• no blood pressure or pulse


• stopping of heart


• swelling of face, fingers, feet, or lower legs


• unconsciousness


• weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Hardening or thickening of skin where the needle is placed


• nausea

Less common

• Anxiety


• dry mouth


• headache


• hyperventilation


• irritability


• nervousness


• restlessness


• shaking


• sleepiness or unusual drowsiness


• trouble sleeping


• vomiting

Rare

• Acid or sour stomach


• belching


• change in taste or bad, unusual, or unpleasant (after) taste


• difficulty having a bowel movement (stool)


• discouragement


• feeling sad or empty


• heartburn


• indigestion


• lack of appetite


• lack or loss of strength


• loss of interest or pleasure


• shoulder pain


• stomach soreness, discomfort, upset, or pain


• stuffy nose


• tiredness


• trouble concentrating


• weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: esmolol Intravenous side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More esmolol Intravenous resources

• Esmolol Intravenous Side Effects (in more detail)
• Esmolol Intravenous Use in Pregnancy & Breastfeeding
• Esmolol Intravenous Drug Interactions
• Esmolol Intravenous Support Group
• 0 Reviews for Esmolol Intravenous - Add your own review/rating

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Eribulin

Pronunciation: ER-i-BUE-lin
Generic Name: Eribulin
Brand Name: Halaven

Eribulin is used for:

Treating breast cancer in certain patients.

Eribulin is a microtubule inhibitor. It works by blocking the growth of cancer cells.

Do NOT use Eribulin if:

• you are allergic to any ingredient in Eribulin


• you have a certain type of irregular heartbeat (congenital long QT syndrome)


• you have used or will be using the medicine palifermin within 24 hours of using Eribulin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Eribulin:

Some medical conditions may interact with Eribulin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have liver or kidney problems, heart problems (eg, heart failure, irregular heartbeat), or low blood electrolyte levels (eg, potassium, magnesium)


• if you have not had previous chemotherapy treatment

Some MEDICINES MAY INTERACT with Eribulin. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Antiarrhythmics (eg, amiodarone, quinidine) or other medicines that may increase the risk of an irregular heartbeat because the risk of irregular heartbeat may be increased. Check with you doctor if you are unsure if any of your medicines might affect your heart rate


• Palifermin because the risk of severe or prolonged mouth or tongue sores may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Eribulin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Eribulin:

Use Eribulin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Eribulin. Talk to your pharmacist if you have questions about this information.


• Eribulin is given as an injection at your doctor's office, hospital, or clinic.


• If you miss a dose of Eribulin, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Eribulin.

Important safety information:

• Eribulin may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Eribulin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Eribulin may cause burning, numbness, or tingling in the hands or feet. This has lasted more than a year in some patients. Discuss any questions or concerns with your doctor. Tell your doctor right away if you develop any of these effects.


• Eribulin may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you have a fever of 100.5 degrees F (38 degrees C) or higher or other signs of infection (eg, sore throat, rash, chills, cough, burning or painful urination).


• Do not receive a live vaccine (eg, measles, mumps) while you are using Eribulin. Talk with your doctor before you receive any vaccine.


• Eribulin may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.


• Women who may become pregnant should use an effective form of birth control while they are using Eribulin. Check with your doctor if you have questions about effective birth control.


• Lab tests, including complete blood cell counts or heart function, may be performed while you use Eribulin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Eribulin should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Eribulin may cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Eribulin while you are pregnant. It is not known if Eribulin is found in breast milk. Do not breast-feed while using Eribulin.

Possible side effects of Eribulin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bone pain; constipation; dizziness; hair loss; headache; joint or muscle aches; loss of appetite; mild weight loss; nausea; tiredness; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); back pain; burning, numbness, or tingling in the hands or feet; depression; irregular heartbeat; mouth or tongue sores or swelling; muscle pain, weakness, or cramps; severe or persistent tiredness or weakness; shortness of breath; swelling of the hands, ankles, or feet; symptoms of infection (eg, fever, chills, cough, sore throat, increased or painful urination); unusual bruising or bleeding.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Eribulin side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Eribulin:

Eribulin is usually handled and stored by a health care provider. If you are using Eribulin at home, store Eribulin as directed by your pharmacist or health care provider. Keep Eribulin out of the reach of children and away from pets.

General information:

• If you have any questions about Eribulin, please talk with your doctor, pharmacist, or other health care provider.


• Eribulin is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Eribulin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Eribulin resources

• Eribulin Side Effects (in more detail)
• Eribulin Use in Pregnancy & Breastfeeding
• Eribulin Drug Interactions
• Eribulin Support Group
• 3 Reviews for Eribulin - Add your own review/rating

• eribulin Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information


• Halaven Prescribing Information (FDA)


• Halaven Consumer Overview

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Inversine

Generic Name: Mecamylamine (mek-ah-MIL-a-meen)
Brand Name: Inversine

Inversine is used for:

Treating severe high blood pressure. It may also be used for other conditions as determined by your doctor.

Inversine is an antihypertensive agent. It works by relaxing and dilating (widening) blood vessels. Blood flows more freely and at a lower pressure through dilated blood vessels, which helps to lower blood pressure.

Do NOT use Inversine if:

• you are allergic to any ingredient in Inversine


• you have heart problems or have recently had a heart attack


• you are taking an antibiotic or sulfonamide (eg, sulfamethoxazole)


• you have glaucoma, certain complications from kidney disease (eg, increased levels of waste products in the blood), or narrowing of the passage from the stomach into the intestine (pyloric stenosis)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Inversine:

Some medical conditions may interact with Inversine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have recently suffered a stroke or you have hardening of the arteries or difficulty urinating due to an enlarged prostate ornarrow bladder neck

Some MEDICINES MAY INTERACT with Inversine. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Urinary alkalinizers because the blood-pressure lowering effects of this drug may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Inversine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Inversine:

Use Inversine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Inversine with food.


• Inversine comes with an additional patient leaflet. Read it carefully and reread it each time you get Inversine refilled.


• Take Inversine on a regular schedule around the clock, unless otherwise directed by your doctor.


• If you miss a dose of Inversine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Inversine.

Important safety information:

• Inversine may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Inversine. Using Inversine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• Inversine may cause dizziness, lightheadedness, or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness.


• Patients being treated for high blood pressure often feel tired or run down for a few weeks after beginning therapy. Continue taking your medication even though you may not feel "normal." Contact your doctor or pharmacist about any new symptoms.


• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Inversine.


• Stop taking Inversine and contact your health care provider at once if frequent loose bowel movements with stomach bloating and decreased gas occur.


• Inversine is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Inversine during pregnancy. It is unknown if Inversine is excreted in breast milk. Do not breast-feed while you are taking Inversine.

Possible side effects of Inversine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; constipation (sometimes preceded by small, frequent liquid stools); decreased sex drive; dizziness; dry mouth; enlarged pupils; impotence;inflammation of the tongue; lightheadedness; loss of appetite; nausea; urinary retention; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal movements; abnormal thinking; difficulty urinating; fainting; frequent loose bowel movements with stomach bloating and decreased gas; seizure; tremors.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Inversine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include anxiety; fainting; irregular heartbeat.

Proper storage of Inversine:

Store Inversine at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Inversine out of the reach of children and away from pets.

General information:

• If you have any questions about Inversine, please talk with your doctor, pharmacist, or other health care provider.


• Inversine is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Inversine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Inversine resources

• Inversine Side Effects (in more detail)
• Inversine Use in Pregnancy & Breastfeeding
• Inversine Drug Interactions
• Inversine Support Group
• 0 Reviews for Inversine - Add your own review/rating

• Inversine Prescribing Information (FDA)


• Inversine Concise Consumer Information (Cerner Multum)


• Inversine Advanced Consumer (Micromedex) - Includes Dosage Information

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