Pronunciation: ER-i-BUE-lin
Generic Name: Eribulin
Brand Name: Halaven
Eribulin is used for:
Treating breast cancer in certain patients.
Eribulin is a microtubule inhibitor. It works by blocking the growth of cancer cells.
Do NOT use Eribulin if:
- you are allergic to any ingredient in Eribulin
- you have a certain type of irregular heartbeat (congenital long QT syndrome)
- you have used or will be using the medicine palifermin within 24 hours of using Eribulin
Contact your doctor or health care provider right away if any of these apply to you.
Before using Eribulin:
Some medical conditions may interact with Eribulin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have liver or kidney problems, heart problems (eg, heart failure, irregular heartbeat), or low blood electrolyte levels (eg, potassium, magnesium)
- if you have not had previous chemotherapy treatment
Some MEDICINES MAY INTERACT with Eribulin. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Antiarrhythmics (eg, amiodarone, quinidine) or other medicines that may increase the risk of an irregular heartbeat because the risk of irregular heartbeat may be increased. Check with you doctor if you are unsure if any of your medicines might affect your heart rate
- Palifermin because the risk of severe or prolonged mouth or tongue sores may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Eribulin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Eribulin:
Use Eribulin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Eribulin. Talk to your pharmacist if you have questions about this information.
- Eribulin is given as an injection at your doctor's office, hospital, or clinic.
- If you miss a dose of Eribulin, contact your doctor right away.
Ask your health care provider any questions you may have about how to use Eribulin.
Important safety information:
- Eribulin may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Eribulin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Eribulin may cause burning, numbness, or tingling in the hands or feet. This has lasted more than a year in some patients. Discuss any questions or concerns with your doctor. Tell your doctor right away if you develop any of these effects.
- Eribulin may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you have a fever of 100.5 degrees F (38 degrees C) or higher or other signs of infection (eg, sore throat, rash, chills, cough, burning or painful urination).
- Do not receive a live vaccine (eg, measles, mumps) while you are using Eribulin. Talk with your doctor before you receive any vaccine.
- Eribulin may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
- Women who may become pregnant should use an effective form of birth control while they are using Eribulin. Check with your doctor if you have questions about effective birth control.
- Lab tests, including complete blood cell counts or heart function, may be performed while you use Eribulin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Eribulin should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Eribulin may cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Eribulin while you are pregnant. It is not known if Eribulin is found in breast milk. Do not breast-feed while using Eribulin.
Possible side effects of Eribulin:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Bone pain; constipation; dizziness; hair loss; headache; joint or muscle aches; loss of appetite; mild weight loss; nausea; tiredness; weakness.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); back pain; burning, numbness, or tingling in the hands or feet; depression; irregular heartbeat; mouth or tongue sores or swelling; muscle pain, weakness, or cramps; severe or persistent tiredness or weakness; shortness of breath; swelling of the hands, ankles, or feet; symptoms of infection (eg, fever, chills, cough, sore throat, increased or painful urination); unusual bruising or bleeding.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Eribulin side effects (in more detail)
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.
Proper storage of Eribulin:
Eribulin is usually handled and stored by a health care provider. If you are using Eribulin at home, store Eribulin as directed by your pharmacist or health care provider. Keep Eribulin out of the reach of children and away from pets.
General information:
- If you have any questions about Eribulin, please talk with your doctor, pharmacist, or other health care provider.
- Eribulin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information is a summary only. It does not contain all information about Eribulin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
More Eribulin resources
- Eribulin Side Effects (in more detail)
- Eribulin Use in Pregnancy & Breastfeeding
- Eribulin Drug Interactions
- Eribulin Support Group
- 3 Reviews for Eribulin - Add your own review/rating
- eribulin Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information
- Halaven Prescribing Information (FDA)
- Halaven Consumer Overview
Compare Eribulin with other medications
- Breast Cancer
- Breast Cancer, Metastatic
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